Early Oxybutinin Treatment for Boys With Posterior Urethral Valves
Status:
Not yet recruiting
Trial end date:
2023-09-10
Target enrollment:
Participant gender:
Summary
Boys with posterior urethral valves have bladder dysfunction of varying severity. Early
treatment of these children with anticholinergics is recommended by some teams, although
there have never been any clear studies on the subject. To our knowledge, no comparative
study of the evolution of valve bladders with or without treatment has been carried out to
date.
Anticholinergic treatment, although it may be beneficial in patients with abnormal bladder
function, such as the neurologic bladders ( in Spina Bifida) for example, may have side
effects and may not be of benefit for this valve population. The evolution of the valves
could be spontaneously favorable.
This study would be the first randomized clinical trial of early therapeutic drug
intervention in the posterior urethral valve population.