Overview

Early Conversion From Tacrolimus to Efalizumab Maintenance Therapy in Kidney Transplant Recipients

Status:
Terminated
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
The toxicity of calcineurin inhibitors(CNI)is a major factor limiting the success of renal transplantation. This protocol aims to replace the calcineurin inhibitor, tacrolimus, with efalizumab early after transplantation in patients with mild impairment of renal function in order to minimize the toxicities of CNI.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Emory University
Collaborator:
Genentech, Inc.
Treatments:
Antibodies, Monoclonal
Tacrolimus