Early Childhood Malaria Prevention With Maloprim in The Gambia
Status:
Completed
Trial end date:
2001-09-01
Target enrollment:
Participant gender:
Summary
A trial was conducted in the 1980s to compare two strategies for control of malaria in young
children aged 3-59 months: treatment with chloroquine versus treatment combined with
fortnightly chemoprophylaxis with Maloprim. The impact on mortality and morbidity was
assessed at the time, and their cognitive abilities and educational outcomes were assess 14
years later in 2001. The hypothesis was that the chemoprophylaxis would reduce morbidity and
mortality and would improve cognitive abilities and educational outcomes in the long term
Phase:
Phase 4
Details
Lead Sponsor:
Imperial College London
Collaborators:
Government of the Gambia London School of Hygiene and Tropical Medicine Medical Research Council Unit, The Gambia Partnership for Child Development Wellcome Trust