Early Amniotomy Versus Delayed Amniotomy Following Foley Catheter Ripening in Nulliparous Labor Induction

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Amniotomy (breaking the bag of water) is commonly used in the induction of labor. However, the timing is highly variable. The purpose of this study is to determine if first time mothers undergoing induction of labor with a Foley catheter experience a decrease in their labor time when undergoing early amniotomy (breaking the bag of water within 1 hour of Foley catheter removal) than when undergoing delayed amniotomy (breaking the bag of water at least 4 hours after Foley catheter removal). Other aims include the relationship between timing of amniotomy and cesarean section, postpartum hemorrhage, intrauterine infection, neonatal Apgar score <7 at 5 minutes, neonatal need for intensive care.

The investigators hypothesize that induction of labor with Foley catheters followed by early amniotomy will result in a decreased duration of labor compared to those who undergo delayed amniotomy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwestern University
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Able to provide informed consent

• English speaking

• Women age 18 years old or greater

• Nulliparous

• Pregnant with a singleton gestation that is greater than or equal to 37 weeks

• Undergoing induction of labor with Foley catheter

Exclusion Criteria:

• Women not meeting above criteria

• Fetus in non-cephalic position

• Intrauterine fetal demise

• Fetus with major anomalies

• HIV, hepatitis B or C infection

• Planned use of oxytocin during the Foley catheter ripening