Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
Status:
Recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
In this clinical trial the effect of early administration of Vitamin C is investigated in
patients admitted at the emergency department with sepsis or septic shock.
When a patient has sepsis, his/her body is causing damage to its own tissues and organs as
result of an infection. This can lead to septic shock. The patient has a low blood pressure,
his/her organs stop working and the patient may even die.
The aim of this trial is to investigate the efficiency of Vitamin C in sepsis and septic
shock. Vitamin C is a vitamin present in various foods and has been approved as dietary
supplement by the Belgian authorities. Over the years it has been proven that Vitamin C is
very safe. In addition, several studies have shown that Vitamin C can also have a protective
effect. It can reduce organ damage and increase survival rates. Although several studies
suggest that Vitamin C can help fight sepsis, it is not yet used in practice. This Belgian
trial, in which several hospitals participate, hopes to provide a clear answer to the
question: "Should Vitamin C be administered to patients admitted in an emergency department
with sepsis or septic shock?"
Phase:
Phase 3
Details
Lead Sponsor:
Universitaire Ziekenhuizen Leuven
Collaborator:
Federaal Kenniscentrum voor Gezondheidszorg, Belgium