EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International)
Status:
Completed
Trial end date:
2018-08-22
Target enrollment:
Participant gender:
Summary
The primary hypothesis being tested in this trial is that ischaemic stroke patients selected
with significant penumbral mismatch (according to imaging criteria) at 4.5 (or 3 hours
depending on local guidelines) - 9 hours post onset of stroke or after 'wake up stroke' (WUS)
will have improved clinical outcomes when given intravenous tissue plasminogen activator
(tPA) compared to placebo.