EWISE: Study of Eplerenone in Women With Chest Pain, Coronary Vascular Dysfunction and Evidence of Myocardial Ischemia
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Some women have chest pain even without having a blockage in one of the major blood vessels
that supplies blood to the heart. In many of these women the microscopic (small) blood
vessels in the heart do not function normally. This study seeks to determine if treatment
with eplerenone, a commercially available diuretic, can improve the function of these
microscopic blood vessels and, possibly, improve the chest pain.
Phase:
Phase 4
Details
Lead Sponsor:
University of Florida
Collaborators:
National Heart, Lung, and Blood Institute (NHLBI) Pfizer