Overview

ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission

Status:
Active, not recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
A randomized, open-label assessor blinded, multi-center, controlled phase III Trial to evaluate the efficacy of AOP2014 administered bi-weekly subcutaneously (s.c.) in preventing molecular relapse (loss of MMR) in CML patients, who discontinue ABL tyrosine kinase inhibitor therapy (TKI) in deep molecular remission of MR4 or better (MR4.5, or MR5).
Phase:
Phase 3
Details
Lead Sponsor:
Philipps University Marburg Medical Center
Collaborators:
AOP Orphan Pharmaceuticals AG
Deutsche Krebshilfe e.V., Bonn (Germany)
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons