EEG-fMRI Experiments During Anesthesia Induction With Propofol
Status:
Recruiting
Trial end date:
2026-09-10
Target enrollment:
Participant gender:
Summary
This observational study aims to investigate healthy cortical and subcortical neural
processes involved in generating intrinsic alpha oscillations during induction of general
anesthesia with propofol. To do this, the investigators have designed a simultaneous
electroencephalogram (EEG)- MRI (functional MRI and Spectroscopy) experiment with a visual
stimulation paradigm that addresses the subject's specific intrinsic alpha rhythm during
anesthesia and wakefulness. The main question it aims to answer is: could the investigators
address the alpha oscillation system of the healthy brain with external stimulation during
anesthesia? This experiment could lead to a better understanding of the mechanisms underlying
the generation of alpha oscillations. It could open new doors to diagnostic and treatment
options for diseases where alpha oscillations, such as post-operative delirium, seem to be
affected.