Overview

Durvalumab (MEDI4736) in Frail and Elder Patients With Metastatic NSCLC (DURATION)

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
AIO-YMO/TRK-0416 (DURATION) is a open-label, treatment stratified and randomized phase II study of Durvalumab, frail or elderly patients with metastatic non-squamous NSCLC with no targetable molecular alterations (EGFRwt; ALKtransl-) and not amenable to cisplatinum-based standard-combination chemotherapy but eligible for at-least mono-chemotherapy with gemcitabine or vinorelbine.
Phase:
Phase 2
Details
Lead Sponsor:
AIO-Studien-gGmbH
Collaborators:
AstraZeneca
Celgene
Treatments:
Antibodies, Monoclonal
Carboplatin
Durvalumab
Gemcitabine
Paclitaxel
Vinorelbine