Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study
Status:
Not yet recruiting
Trial end date:
2027-06-01
Target enrollment:
Participant gender:
Summary
This multicentre, adaptive, pragmatic, double-blind, three-arm, placebo-controlled,
randomised, non-inferiority clinical trial will compare the incidence of surgical site
infection and other healthcare associated infections, health economic and microbiological
impact after intraoperative only (Arm A), to 24 hours (Arm B) and, to 48 hours (Arm C) of IV
cefazolin and placebo postoperative surgical antimicrobial prophylaxis in patients undergoing
cardiac surgery