Duration and Depth of Anesthesia Induced by a Bolus of Etomidate
Status:
Completed
Trial end date:
2022-04-20
Target enrollment:
Participant gender:
Summary
Induction of general anesthesia requires to be safe and to ensure a proper level of
anesthesia. A proper anesthesia is sufficient to guarantee loss of consciousness and amnesia
and without being too depth leading to a electroencephalogram (EEG) with burst suppression.
The depth of anesthesia is monitored by the bispectral index analyse of the EEG, this allows
to detect any under- or over-dose of anesthesia. The monitoring works with an unknown
algorithm (patent), which evaluate the state of consciousness in the patient.
Etomidate and propofol are commonly use to ensure general anesthesia. Actually, really few
litterature has objective informations about the monitoring of Etomidate. The few existant
are the old ones and has just a clinical evaluation of the depth of anesthesia (loss of
consciousness, loss of breathing, loss of palpebral reflex). Except the fact that these
clinical evaluations come from the brain stem, and in fact are not reliable to assess the
cortical activity which is reduced by etomidate.
Therefore, some anesthetists are fearful that etomidate is not sufficient to ensure a proper
anesthesia to intubate the patient.
This interventionnal study has two purpose. Firstly, a survey will be conduct about the
habits and beliefs when use of etomidate.
Secondly, a prospective study will be conduct to monitore with the bispectral index the depth
and duration of anesthesia with etomidate.