Overview

Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
The investigators will investigate the efficacy of dupilumab in patients with severe eosinophilic CRSsNP who are resistant to the conventional treatment with intranasal corticosteroids and have significantly extensive disease involving more than 2 sinuses bilaterally in sinus CT scan and Lund-Mackay sinus (LMK) CT score >=10 at baseline.
Phase:
Phase 2
Details
Lead Sponsor:
University of South Florida
Treatments:
Antibodies, Monoclonal