Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis
Status:
Recruiting
Trial end date:
2022-08-17
Target enrollment:
Participant gender:
Summary
Primary Objective:
- Assess change in neuronal architecture following long term treatment with dupilumab in
skin biopsies from atopic dermatitis (AD) participants with chronic pruritus
Secondary Objectives:
- Assess change in neuronal architecture following short term treatment with dupilumab and
during follow-up in skin biopsies from AD participants with chronic pruritus
- To evaluate the efficacy of dupilumab in AD participants with chronic pruritus
- To evaluate the safety of dupilumab in adult participants with moderate-to-severe AD