Duloxetine for Acute Post-mastectomy Pain

• Status: Completed
• Trial end date: 2020-02-10
• Target enrollment: 0
• Participant gender: Female

Summary

The objective of this study is to evaluate the analgesic effect of oral dulexitine tablet (administered 2 h before surgery) as well as the ideal dose for acute postmastectomy pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Duloxetine Hydrochloride

Criteria

Inclusion Criteria:

• Adult females scheduled for unilateral MRM with axillary evacuation for breast cancer,

• American Society of Anesthesiologists physical status (ASA) class I and II

Exclusion Criteria:

• Patients with a known allergy to Duloxetine or morphine,

• A history of drug or alcohol abuse,

• Patients with impaired kidney or liver functions,

• Patients with chronic pain or regularly receiving analgesics,

• Any psychiatric illness that would interfere with the perception and the assessment of pain.

• Any reason that resulted in the protocol violation.