Overview

Duloxetine Versus Placebo for Osteoarthritis Knee Pain

Status:
Completed
Trial end date:
2007-10-01
Target enrollment:
0
Participant gender:
All
Summary
The primary purpose of this study is to determine if duloxetine reduces pain severity in patients with osteoarthritis knee pain.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Eli Lilly and Company
Treatments:
Duloxetine Hydrochloride
Criteria
Inclusion Criteria:

- Male or female outpatients with osteoarthritis knee pain.

Exclusion Criteria:

- Cardiovascular, hepatic, renal, respiratory, or hematologic illness, or other medical
or psychiatric condition that, in the opinion of the investigator, would compromise
participation or be likely to lead to hospitalization during the course of the study.

- Acute liver injury (such as hepatitis) or severe cirrhosis.

- Previous exposure to duloxetine.

- Body Mass Index (BMI) over 40.

- Major depressive disorder.

- Daily use of narcotics.