Duloxetine Potentiates the Analgesic Efficacy of Intrathecal Morphine
Status:
Completed
Trial end date:
2020-03-14
Target enrollment:
Participant gender:
Summary
Duloxetine is a serotonin-norepinephrine reuptake inhibitor primarily used for treatment of
major depression and anxiety. Duloxetine also has been used in the treatment of chronic pain
conditions, such as osteoarthritis and musculoskeletal pain. There are few studies examining
its effect for acute pain. The objective of this study is to evaluate the analgesic effect of
duloxetine combined with intrathecal morphine for patients subjected to major abdominal
cancer surgery