The widespread availability of efficient contraception as well as women's increased education
has led to childbearing postponement. Combined with the increased recognition of the concept
of "ovarian aging", this has opened the Pandora´s box of EOC, which is currently considered a
safe and cost-efficient approach among assisted reproduction techniques.
Previous studies have shown that two main factors determine the CLBR after EOC: 1) patient's
age at the time of oocyte banking, and 2) the number of oocytes retrieved. Therefore,
measures aiming at increasing the oocyte yield, specially the number of mature oocytes
retrieved, will maximize the success of this technique.
In the last few years, the dual trigger for final oocyte maturation has emerged has an
approach that seems to improve both oocyte yield and quality when compared to the hCG trigger
alone. Nowadays, the standard of care in EOC patients is final oocyte maturation with a
single bolus of GnRH-a. Understanding the impact of the dual trigger on the number of MII
oocytes retrieved in patients undergoing EOC will improve the treatment protocols and allow
for a better patient counselling.