Overview

Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial

Status:
Terminated
Trial end date:
2016-11-04
Target enrollment:
Participant gender:
Summary
To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when combined with pre-operative capecitabine and radiotherapy in patients with locally advanced rectal cancer.
Phase:
Phase 1
Details
Lead Sponsor:
The Christie NHS Foundation Trust
Collaborators:
AstraZeneca
Cancer Research UK
Treatments:
Capecitabine
Cediranib