Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 Diabetes
Status:
Completed
Trial end date:
1999-07-01
Target enrollment:
Participant gender:
Summary
OBJECTIVES:
I. Establish a long-term working relationship between clinical investigators and the
Minnesota American Indian community.
II. Compare the effectiveness of lisinopril (an angiotensin-converting enzyme inhibitor) and
nifedipine (a calcium channel blocker) in preventing nephropathy and vascular disease in
Minnesota American Indians with non-insulin-dependent diabetes mellitus and microalbuminuria.
III. Compare the effectiveness of simvastatin (a 3-hydroxy-3-methylglutaryl coenzyme A
reductase inhibitor) with lipid-lowering strategies recommended by the National Cholesterol
Education Program in preventing nephropathy and vascular diseases in these patients.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)