Drug-drug-interaction Study of Ramipril, Amlodipine and Atorvastatin
Status:
Completed
Trial end date:
2019-03-26
Target enrollment:
Participant gender:
Summary
Study to determine the potential pharmacokinetic interaction of ramipril (and ramiprilat),
atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at
steady state after a multiple oral administration and to monitor the safety of the
co-administration of these drugs. This study aims to determine if the steady state study
pharmacokinetic parameters of any of the given drugs and the tolerability is altered when
administered concomitantly.
Phase:
Phase 1
Details
Lead Sponsor:
Midas Pharma GmbH
Treatments:
Amlodipine Amlodipine, atorvastatin drug combination Atorvastatin Ramipril