Overview

Drug-drug Interaction Study of Gepotidacin

Status:
Completed
Trial end date:
2020-12-21
Target enrollment:
Participant gender:
Summary
This study is a drug-drug interaction (DDI), pharmacokinetics (PK), safety and tolerability study in adult healthy participants, including Japanese cohort. This study is designed to assess co-administration of probe substrates with gepotidacin in study cohorts 1 to 3 and establishing PK and safety in Japanese participants in cohort 4. Food effect will also be evaluated in cohort 4.
Phase:
Phase 1
Details
Lead Sponsor:
GlaxoSmithKline
Treatments:
Cimetidine
Digoxin
Midazolam
Rifampin