Drug-drug Interaction (DDI) With a P-gp Inhibitor, Organic Anion Transporting Polypeptide OATP-inhibitor, Food Effect
Status:
Completed
Trial end date:
2017-05-31
Target enrollment:
Participant gender:
Summary
The primary objective of this trial is to investigate the relative bioavailability of BI
685509 given alone under fasted conditions (Reference, R) compared to the intake after a high
fat, high caloric breakfast (Test 1, T1), to combined administration with itraconazole under
fasted conditions (Test 2, T2) and to combined administration with rifampin under fasted
conditions (Test 3, T3).
The secondary objective is the evaluation and comparison of several pharmacokinetic
parameters between the treatments.