Drug Treatment for Pathologic Gambling Disorder

• Status: Completed
• Trial end date: 2005-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will establish the best dose of the drug naltrexone to treat patients with Pathological Gambling Disorder (PGD) and severe urge symptoms.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Chicago
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Naltrexone

Criteria

Inclusion Criteria:

• Diagnostic and Statistical Manual IV criteria for Pathological Gambling Disorder

• Moderate or severe gambling urge assessed by the Gambling Symptom Assessment Scale

• No psychiatric drug use for 2 weeks or more

• Score >= 5 on The South Oaks Gambling Screen

• Hamilton Depression Rating Scale and Anxiety Rating score < 26. An increase (up to 10 points) of the scores is allowed unless the subject shows the risks of suicide.

• Completion of complete blood count, urinalysis, liver and thyroid function tests, and pregnancy tests, with no evidence of significant lab abnormalities

• Reliable birth control in women of child-bearing potential