Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder
Status:
Completed
Trial end date:
2019-04-05
Target enrollment:
Participant gender:
Summary
The overall goal of this project is to develop initial human data on effects of novel
compounds on safety (interactions with oxycodone) and efficacy (subjective response to
oxycodone) in non-treatment seeking opioid use disorder subjects. The compound to be studied
will be the 5-HT2CR agonist lorcaserin. There are no known or reported adverse interactions
between lorcaserin and oxycodone or other opioids.