Drug Drug Interaction Study Of Crizotinib With Esomeprazole.
Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
This is an open-label, randomized, cross-over, single dose study in healthy volunteers to
evaluate the potential effect of esomeprazole, a proton pump inhibitor, on the
pharmacokinetics of crizotinib. Each subject enrolled will receive two single oral doses of
crioztinib with or without esomeprazole separated by a washout period of at least 14 days.