Overview

Drug Delivery Devices for Osteomyelitis

Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
0
Participant gender:
All
Summary
Fifty-one patients suffering from chronic post-traumatic or postoperative osteomyelitis of the lower extremities were included in the retrospective investigation. The patients were assigned to the study group of the combination therapy with antibiotic-loaded calcium sulfate and antibiotic-loaded PMMA or the control group of the antibiotic-loaded PMMA. Hematological parameters, eradication of infection, rate of infection recurrence and reoperation rate were evaluated during the follow-up.
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Yulin Orthopedics Hospital of Chinese and Western Medicine
Treatments:
Anti-Bacterial Agents
Antibiotics, Antitubercular
Calcium
Calcium, Dietary
Polymethyl Methacrylate
Vancomycin
Criteria
Inclusion Criteria:

- The retrospective study included patients with chronic post-traumatic or postoperative
osteomyelitis and excluded patients suffering from hematogenous osteomyelitis or acute
post-traumatic or postoperative osteomyelitis.

Exclusion Criteria:

- Other kinds of osteomyelitis.