Dried Plums (Prunes) vs. Polyethylene Glycol 4000 for Treatment of Functional Constipation in Children
Status:
Unknown status
Trial end date:
2020-11-01
Target enrollment:
Participant gender:
Summary
Children with functional constipation according to the Rome IV criteria will be randomly
assigned to receive prunes at dose 3.5 g/kg/d (prune group) or Polyethylene Glycol 4000 (PEG
group) at dose 0.5 g/kg/d for 4 weeks. Before treatment children with impaction will receive
PEG 4000 at the dose 1.5 g/kg for 3-5 consecutive days. The primary outcome measure will be
treatment success, defined as ≥3 BM per week with no fecal soiling during last week of the
intervention.