Doxorubicin or Epirubicin and Cyclophosphamide in Treating Older Women With Invasive Breast Cancer
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, epirubicin, and cyclophosphamide,
work in different ways to stop the growth of tumor cells, either by killing the cells or by
stopping them from dividing. Giving combination chemotherapy after surgery may kill any tumor
cells that remain after surgery. Sometimes, after surgery, the tumor may not need more
treatment until it progresses. In this case, observation may be sufficient. It is not yet
known whether giving doxorubicin or epirubicin together with cyclophosphamide is more
effective than observation in treating older women with invasive breast cancer.
PURPOSE: This randomized phase III trial is studying doxorubicin or epirubicin and
cyclophosphamide to see how well they work compared with observation in treating older women
with invasive breast cancer.