Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles

• Status: Recruiting
• Trial end date: 2021-02-02
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in patients with history of poor oocytes yield, despite normal response to COH, due to low (<50%) number of oocytes retrieved per number of follicles > 14 mm in diameter on day of hCG administration

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Riyadh Fertility and Reproductive Health center

Criteria

Inclusion Criteria:

• Patients with history of poor oocytes yield in previous IVF attempt, despite normal response to COH, due to low (<50%) number of oocytes retrieved per number of follicles > 14 mm in diameter on day of hCG administration

• Patients with 6 to 15 mature follicles on the day oocyte trigger in the current IVF-ET attempt

Exclusion Criteria:

• Endometriosis

• PCOS