Double Stimulation Followed by a Fresh Embryo Transfer
Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
The major goal of controlled ovarian stimulation (COS) is to increase the number of oocytes
harvested in order to result in the generation of a higher number of available embryos,
extended embryo culture, embryo selection and finally providing higher cumulative live birth
rates in infertile patients. Moreover, with the idea of the multiple waves of follicular
production, we could start to take full advantage of the whole follicular cohort, and not
only of the follicular wave.
In the context of low prognosis women such as women with poor ovarian response where, the
success rates are very low due to the low number of oocytes retrieved and consequently of
viable embryos), Dual stimulation may be of great value as a tool to improve outcomes.
The reported advantage of DuoStim is retrieved of more oocytes within a shorter time span,
resulting in an increase in the probability of having transferable embryos increases, and
theoretically reducing time to live birth as well as cycle cancellation.