Double Blind Crossover Comparison of Diuretics in the Young
Status:
Unknown status
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
The principle objective of the study is to determine whether low-renin (i.e. salt sensitive)
hypertension at a young age is caused by the kidneys hanging onto too much salt as a result
of an over active salt pump in the kidney.
The kidneys have four different salt pumps, and each is blocked by a different type of
diuretic (salt losing tablet)If one out of the four is overactive, we would expect patients
to respond much better to one diuretic than to the alternatives - rather than responding
equally well to all available types of diuretic.