Dose of Norepinephrine and the Concentration of L-Lactate in the Rectum and Stomach in Patients With Septic Shock.
Status:
Completed
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
Norepinephrine is a drug used to increase blood pressure in patients with life-threatening
infection. However, norepinephrine may limit the bloodflow to the gut, thereby causing
relative lack of oxygen to the cells. This leads to increased formation of lactic acid.
This study examines whether increasing the dose of norepinephrine leads to higher
concentrations of lactic acid in the rectum and stomach in patients with life-threatening
infection.