Overview

Dose-adjusted Adjuvant FEC Compared to Standard FEC for Breast Cancer

Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
This is an open randomized phase III study. The primary objective of this study is to compare FEC adjuvant chemotherapy in operable breast cancer given either as fixed doses calculated according to the patients surface area or with doses adjusted according to leukopenia after course one in order to achieve hematological equitoxicity. The main aim of the study is to test whether chemotherapy dosage aimed at hematological equitoxicity will improve the effect of adjuvant chemotherapy.
Phase:
Phase 3
Details
Lead Sponsor:
Henrik Lindman
Collaborators:
Danish Breast Cancer Cooperative Group
Danish Breast Cancer Group
Pharmacia Pharmaceutical Company
Scandinavian Breast Cancer Group
Scandinavian Breast Group
Swedish Breast Cancer Association
Swedish Breast Cancer Group
Swedish Cancer Foundation
Swedish Cancer Society
Uppsala University Oncology Department Trust
Treatments:
Cyclophosphamide
Epirubicin