Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder
Status:
Completed
Trial end date:
2018-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to examine the efficacy of 50 mg of d-cycloserine in comparison
to placebo (a pill containing no medication) for improving the effectiveness of
cognitive-behavioral therapy (CBT) in reducing symptoms associated with social anxiety
disorder. In addition, the study will examine whether the effectiveness of d-cycloserine
depends on the timing of the pill administration (i.e., 1- hour before the session or
immediately after the session) as well as the success of the CBT therapy sessions. The
investigators hypothesize that the tailored post-session DCS administration condition will
outperform the other conditions (pre-session DCS, placebo, and non-tailored post-session
DCS). This will be evidenced by short- and long-term improvements in social anxiety severity.
Phase:
Early Phase 1
Details
Lead Sponsor:
University of Texas at Austin
Collaborators:
Boston University Rush University Medical Center Southern Methodist University