Overview Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism Status: Completed Trial end date: 2018-04-01 Target enrollment: Participant gender: Summary This study is designed to answer the question as to whether the sympathetic nervous system is an important determinant of bone metabolism in humans. Phase: Early Phase 1 Details Lead Sponsor: Mayo ClinicTreatments: Adrenergic beta-AntagonistsAtenololNebivololPropranolol