Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children
Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
Dose-finding study to compare intranasal midazolam doses of 0.2, 0.3, 0.4 and 0.5 mg/kg in
children undergoing laceration repair to achieve the following aims:
Specific Aim #1: To determine the most effective dose of intranasal midazolam for producing
adequate sedation state and time to onset of minimal sedation associated with each dose.
Specific Aim #2: To determine the time to recovery and describe the adverse events associated
with each dose.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Columbia University
Collaborators:
Emergency Medicine Foundation Mailman School of Public Health