Dose Effect of Tranexamic Acid on the Incidence of Deep Venous Thrombus in Cardiac Surgery
Status:
Unknown status
Trial end date:
2020-03-31
Target enrollment:
Participant gender:
Summary
In recent years, the lysine analogs tranexamic acid (TXA) has gained wide use in cardiac
surgery as a blood-sparing agent. However, the safety of the drug and its impact on overall
outcomes of cardiac surgery remains debated. The current study evaluates the dose effect of
TXA on the incidence of deep venous thrombus (DVT) in cardiac surgery with cardiopulmonary
bypass. Also, the dose effect of TXA on bleeding and allogeneic transfusion is evaluated.