Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria
Status:
Terminated
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
Intrarenal calcifications (nephrocalcinosis) is present in Dent's disease and likely
contribute to progression toward renal failure. In order to prevent this complication it is
usually proposed to treat affected patients during childhood with high doses of thiazides.