Dose Dense MVAC for Muscle Invasive Bladder Cancer
Status:
Completed
Trial end date:
2013-08-07
Target enrollment:
Participant gender:
Summary
Standard treatment for early stage bladder cancer is chemotherapy with methotrexate (M),
vinblastine (V), adriamycin (A), and cisplatin (C) followed by surgical removal of any
remaining cancer and the bladder with the intent of cure. The M V chemotherapy is usually
given every 14 days with the AC given along each 28 days. This study looks at giving the same
drugs at the same doses closer together, all drugs every 14 days, with the support of growth
factor medication to promote growth of the white blood cells and platelets and allow
chemotherapy to be finished sooner and surgery to be done sooner.