Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Giving chemotherapy, such as fludarabine, busulfan, and etoposide, before a donor
umbilical cord blood stem cell transplant helps stop the growth of cancer cells. When the
healthy stem cells from a donor are infused into the patient they may help the patient's bone
marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the
transplanted cells from a donor can make an immune response against the body's normal cells.
Giving antithymocyte globulin before transplant and tacrolimus and prednisone after
transplant may stop this from happening.
PURPOSE: This phase I trial is studying how well donor umbilical cord blood transplant works
in treating patients with advanced hematologic cancer.