Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis

• Status: Completed
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study questions whether low-dose ferrous sulfate taken by mouth daily for 6 weeks increases hemoglobin concentration in adult subjects with cystic fibrosis and hypoferremic anemia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dartmouth-Hitchcock Medical Center

Criteria

Inclusion Criteria:

• History of Pseudomonas aeruginosa colonization of the lung

• Transferrin saturation (TSAT) less than or equal to 21%

• Hemoglobin concentration <15.5 gm/dl (men)

• Hemoglobin concentration <13.6 gm/dl (women)

Exclusion Criteria:

• Use of iron-containing vitamin or supplement

• Pregnancy

• Lactation

• Cirrhosis

• History of chronic visible (gross) hemoptysis

• Hereditary hemochromatosis

• History of transfusion-related iron overload

• Use of iron chelator(s)

• Withdrawal of informed consent

• Contraindication to phlebotomy