Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?
Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
Adolescent girls with androgen excess have a higher rate of irregular periods and decreased
ovulation rates compared to normal girls, and are considered at-risk for developing
polycystic ovary syndrome (PCOS). This pilot study will look at whether giving spironolactone
might improve ovulation rates in girls with androgen excess, ages 13-19. If this is true,
spironolactone treatment to young girls might prevent PCOS from developing and avoid future
infertility.