Does Thiamine Help Vomiting and Nausea in Pregnancy?

• Status: Terminated
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed. Thiamine is given to prevent wernicke encephalopathy. This research try to find out whether thiamine helps the vomiting and nausea as well, by comparing the response to thiamine and promethazine in women who suffer from nausea and vomiting in pregnancy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: HaEmek Medical Center, Israel
• Treatments: Diphenhydramine; Promethazine; Thiamine

Criteria

Inclusion Criteria:

• Pregnant women until 12th week of gestation

• The women visit the ER because of nausea and vomiting

• The women didn't received thiamine yet

Exclusion Criteria:

• Pregnant women over 12th week of gestation

• Women that received thiamine before

• women that allergic to the studied drugs