Does Small Intestinal Bacterial Overgrowth Contribute to Functional Dyspepsia
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The prevalence of functional dyspepsia (FD) is estimated to be 15% of the adult population.
FD is commonly described as a condition of chronic abdominal discomfort localized to the
upper abdomen. Postprandial bloating, pain, nausea, vomiting, belching, and early satiety are
common symptoms of the FD patient. FD is defined by >12 weeks of symptoms, which need not be
consecutive, within the preceding year consisting of a) persistent or recurrent dyspepsia and
b) an absence of organic disease after a gastrointestinal endoscopy or x-ray series. FD is
therefore considered a disorder of function because no mucosal pathology is seen in these
patients, as in patients with other functional disorders such as irritable bowel syndrome
(IBS) and fibromyalgia (FM). There is a remarkable degree of overlap among these three
disorders. These 3 disorders share the finding of hypersensitivity and the symptom of
postprandial bloating to suggest the possibility of a common origin.