Does Perineural Dexamethasone Prolong Duration of a Nerve Block?

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to investigate whether dexamethasone as an adjuvant to ropivacaine for adductor canal block increases duration of the sensory block, when controlling for a systemic effect using a paired design and bilateral blocks.

The investigators hypothesize that adding dexamethasone to ropivacaine will prolong block duration compared with ropivacaine + placebo.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists class 1

• Body Mass Index 18-30

Exclusion Criteria:

• Allergy to study medication

• Earlier trauma or surgery to lower limb

• Diabetes Mellitus

• Alcohol or drug abuse

• Daily intake of opioids or steroids last 4 weeks

• Daily intake of any analgesics last 48 hours