Does Icodextrin Reduce the Risk of Small Bowel Obstruction?

• Status: Active, not recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims at investigating if icodextrin 4% instilled in abdominal cavity during surgery can reduce the risk of surgery and hospitalisation for small bowel obstruction in patients with colorectal cancer. Follow-up data is collected from the Swedish national colorectal cancer registry.Patients are followed for 5 years postoperatively.The study is a randomized Swedish multicenter study and planned to include 1,800 patients. A safety control is planned after 300 included patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Uppsala University
• Treatments: Icodextrin

Criteria

Inclusion Criteria:

• Colorectal cancer

• Curative surgery planned

• Informed consent

• Age 18-85

Exclusion Criteria:

• Local surgery planned

• Generalized disease

• Other malignancy

• Not informed consent