Overview

Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?

Status:
Completed
Trial end date:
2020-02-20
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine whether IV acetaminophen can decrease the need for subsequent opioid administration in the acute management of sickle cell crisis pain in the pediatric emergency room.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Newark Beth Israel Medical Center
Treatments:
Acetaminophen
Analgesics, Opioid
Criteria
Inclusion Criteria:

- Any patient age 4-16 years with sickle cell disease who presents the Pediatric ER with
acute sickle cell pain crisis with a pain of 6/10 or higher

Exclusion Criteria:

- Patient with fever (38C or 100.4F)

- Patient less than age 4 years

- Patient greater than age 16 years

- Patient with hypersensitivity/allergy to either morphine, NSAIDs, or acetaminophen

- Patient received acetaminophen within the past 4 hours

- Patient with known liver disease or renal disease

- Patient not requiring IV morphine (pain score 5/10 or less)

- Patient enrolled in the study within the past 72 hours