Does Botulinum A Toxin Help With Pain From Rotator Cuff Arthropathy?
Status:
Completed
Trial end date:
2017-11-22
Target enrollment:
Participant gender:
Summary
Rotator cuff arthropathy is a cause of shoulder arthritis which is a common condition seen
both in primary and secondary care. It is a painful condition, with significant disability.
Specialist shoulder replacements have found acceptance within the trust, nationally and
internationally although there are high complication rates. There is however a significant
cost difference (fifty fold) between a reverse total shoulder replacement and a botox
injection, and to date there have been no randomised control trials, or any registered,
comparing the use of a botox injection for pain relief in cuff arthropathy versus no
treatment. If there is a significant clinical difference in the pain outcomes between the
two, this could result in significant savings to the NHS and the taxpayer as a whole. If high
levels of pain relief could be predictably obtained using Botulinum A toxin injections then
potentially patients could avoid the need for surgery.
Phase:
Phase 2
Details
Lead Sponsor:
Royal Devon and Exeter NHS Foundation Trust
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA