Does Alkalinization Reduce Perceived Pain Levels During Sentinel Lymph Node Imaging?
Status:
Completed
Trial end date:
2016-12-30
Target enrollment:
Participant gender:
Summary
Pain during nuclear medicine breast lymphnode detection procedures has been reported as high
as 8.8/10. Using Sodium Bicarbonate to alkalinize the radio-pharmaceutical injection, pain
can safely be reduced from 6.6/10 to 4.7/10, during breast lymph node detection procedures.
In sites other then the breast, using Bicarbonate to make the injection's pH closer to
natural, attempts to lower the pain levels will be performed.
Hypothesis: The perceived pain level during non breast sentinel lymph node techniques can be
reduced by raising the pH of the injectate (Tc-99m SC) to near the physiologic level of pH
7.40.
Phase:
N/A
Details
Lead Sponsor:
University of Arkansas
Collaborators:
Howard J Barnhard, Resident Research Endowment. UAMS DEPT of Radiology.